The INTErnational Gamma-Ray Astrophysics Laboratory (INTEGRAL) is a space telescope for observing gamma rays of energies up to 8 MeV. It was launched by the European Space Agency (ESA) into Earth orbit in 2002, and is designed to provide imaging and spectroscopy of cosmic sources. In the MeV energy range, it is the most sensitive gamma ray observatory in space. It is sensitive to higher energy photons than X-ray instruments such as NuSTAR, the Neil Gehrels SWIFT Observatory, XMM-Newton, and lower than other gamma-ray instruments such Fermi and HESS.

Photons in INTEGRAL's energy range are emitted by relativistic and supra-thermal particles in violent sources, radioactivity from unstable isotopes produced during nucleosynthesis, X-ray binaries, and astronomical transients of all types, including gamma-ray bursts. The spacecraft's instruments have very wide fields of view, which is particularly useful for detecting gamma-ray emission from transient sources as they can continuously monitor large parts of the sky.

INTEGRAL is an ESA mission with additional contributions from European member states including Italy, France, Germany, and Spain. Cooperation partners are the Russian Space Agency with IKI and NASA.