Soyuz TMA-05M was the 114th flight of a Soyuz spacecraft. It was launched on 15 July 2012, transporting three members of the Expedition 32 crew to the International Space Station (ISS). The Soyuz remained docked to the ISS throughout the mission to serve as an emergency escape vehicle. The launch also coincided with the 37th anniversary of the Apollo–Soyuz Test Project. Soyuz TMA-05M successfully returned to Earth on 19 November 2012.

The Soyuz is a Soviet crewed spacecraft, developed to perform lunar missions with crew. This version called 7K will fly 4 times on the giant launcher N1, and several tens of times on Proton to fly over the Moon, which will be successful during the mission Zond 4. Soyuz will become the first spacecraft to transport living beings on the Moon during the flight of Zond 5, with two turtles. Thereafter, it is adapted to the low orbit and will fly on the Soyuz launcher to supply the Soviet Salyut and Mir stations, and the ISS.