Soyuz TMA-03M was a spaceflight to the International Space Station (ISS). It launched on 21 December 2011 from Site One at the Baikonur Cosmodrome, Kazakhstan, carrying three members of Expedition 30 to the ISS. TMA-03M was the 112th flight of a Russian Soyuz spacecraft, since the first in 1967, and the third flight of the modernised Soyuz-TMA-M version. The docking with the International Space Station took place at 19:19 Moscow Time on 23 December, three minutes ahead of schedule.

The crew were Oleg Kononenko (Russia, commander), André Kuipers (the Netherlands) and Donald Pettit (United States). The Soyuz remained aboard the space station for the Expedition 30 increment to serve as an emergency escape vehicle if needed.

The Soyuz is a Soviet crewed spacecraft, developed to perform lunar missions with crew. This version called 7K will fly 4 times on the giant launcher N1, and several tens of times on Proton to fly over the Moon, which will be successful during the mission Zond 4. Soyuz will become the first spacecraft to transport living beings on the Moon during the flight of Zond 5, with two turtles. Thereafter, it is adapted to the low orbit and will fly on the Soyuz launcher to supply the Soviet Salyut and Mir stations, and the ISS.