Soyuz TMA-13 (Russian: Союз ТМА-13, Union TMA-13) was a Soyuz mission to the International Space Station (ISS). The spacecraft was launched by a Soyuz-FG rocket at 07:01 GMT on 12 October 2008. It undocked at 02:55 GMT on 8 April 2009, performed a deorbit burn at 06:24, and landed at 07:16. By some counts, Soyuz TMA-13 is the 100th Soyuz spacecraft to be crewed.

The Soyuz is a Soviet crewed spacecraft, developed to perform lunar missions with crew. This version called 7K will fly 4 times on the giant launcher N1, and several tens of times on Proton to fly over the Moon, which will be successful during the mission Zond 4. Soyuz will become the first spacecraft to transport living beings on the Moon during the flight of Zond 5, with two turtles. Thereafter, it is adapted to the low orbit and will fly on the Soyuz launcher to supply the Soviet Salyut and Mir stations, and the ISS.