Soyuz TMA-1, also catalogued as Soyuz TM-35, was a 2002 Soyuz mission to the International Space Station (ISS) launched by a Soyuz FG launch vehicle with a Russian-Belgian cosmonaut crew blasted off from the Baikonur Cosmodrome in Kazakhstan. This was the fifth Russian Soyuz spacecraft to fly to the ISS. It was also the first flight of the TMA-class Soyuz spacecraft. Soyuz TM-34 was the last of the prior Soyuz-TM spacecraft to be launched.

The Soyuz is a Soviet crewed spacecraft, developed to perform lunar missions with crew. This version called 7K will fly 4 times on the giant launcher N1, and several tens of times on Proton to fly over the Moon, which will be successful during the mission Zond 4. Soyuz will become the first spacecraft to transport living beings on the Moon during the flight of Zond 5, with two turtles. Thereafter, it is adapted to the low orbit and will fly on the Soyuz launcher to supply the Soviet Salyut and Mir stations, and the ISS.