The Soyuz MS-21 spacecraft with cosmonauts Oleg Artemyev, Denis Matveev and Sergey Korsakov will undock from the International Space Station for its return to Earth.

After a six-month stay on the International Space Station, cosmonauts Oleg Artemyev, Denis Matveev and Sergey Korsakov will return to Earth, ending the MS-21 mission.

The Crew Dragon Endurance crew spacecraft will dock at the International Space Station with the Crew-5 mission composed of NASA astronauts Nicole Mann and Josh Cassada, JAXA astronaut Koichi Wakata and Russian cosmonaut Anna Kikina.

The Crew Dragon Freedom crew spacecraft will undock from the International Space Station with the Crew-4 mission composed of NASA astronauts Kjell Lindgren, Bob Hines and Jessica Watkins, and ESA astronaut Samantha Cristoforetti. After separation, the spacecraft will return to Earth.

The Crew Dragon Freedom crew ship will splashdown in the ocean with the Crew-4 mission composed of NASA astronauts Kjell Lindgren, Bob Hines and Jessica Watkins, and ESA astronaut Samantha Cristoforetti after a six-month stay on the International Space Station.

After a nearly five-month journey from Earth, NASA's CAPSTONE spacecraft will reach final operational orbit around the Moon where it will validate technologies for the future Gateway space station of the Artemis program.

The OSIRIS-REx spacecraft will return a sample of the asteroid Bennu to Earth. The sample will land via parachute in the Utah desert.