Cargo Dragon CRS-25 will undock autonomously from the Harmony module on the International Space Station after a one-month stay, orbit the Earth and then splash down in the Gulf of Mexico or the Atlantic Ocean.

The DART spacecraft will achieve the kinetic impact deflection by deliberately crashing itself into Dimorphos at a speed of approximately 6.6 km/s. LICIACube will be carrying out observational analysis after DART's impact.

After a nearly five-month journey from Earth, NASA's CAPSTONE spacecraft will reach final operational orbit around the Moon where it will validate technologies for the future Gateway space station of the Artemis program.

The OSIRIS-REx spacecraft will return a sample of the asteroid Bennu to Earth. The sample will land via parachute in the Utah desert.