The Soyuz MS-11 spacecraft will land in Kazakhstan with crew members Anne McClain, David Saint-Jacques, and Oleg Kononenko after a seven-month stay at the International Space Station.

NASA will conduct an in-flight abort test of its Orion space capsule. The test will ensure that the capsule is capable of safely carrying crew away from the launch vehicle in the event of an anomaly.

Boeing's CST-100 Starliner capsule will perform a pad abort test as part of NASA's Commercial Crew program.

The core stage for NASA's first SLS rocket will perform a Green Run hotfire test on the B-2 test stand at NASA Stennis

Callisto is the first reusable launcher prototype of the European Space Agency, which will be used to develop the launcher that will succeed Ariane 6, Ariane Next. It will take off from the Kourou base in French Guiana for a suborbital flight, before returning to land next to his launch pad.

OSIRIS-REx will move into position to collect a sample of asteroid Bennu's surface material. The spacecraft's sampling arm will then touch the surface for five seconds as part of the Touch-And-Go (TAG) sampling maneuver.

After collecting several samples of the asteroid Ryugu, and after dropping several objects on its surface, Hayabusa-2 will leave Ryugu in December 2019 to bring back the samples it has collected on the asteroid. The capsule containing them should land in the Australian desert just like the Hayabusa-1 mission.

NASA's Mars 2020 Mars rover will land at Jezero crater on Mars. The mission will seek signs of habitable conditions on Mars in the ancient past, and will also search for evidence—or biosignatures—of past microbial life.

ExoMars is a Martian rover of the European Space Agency that will land in the region of Oxia Planum. The rover will investigate the local geology and search for signs of past and present life.

The OSIRIS-REx spacecraft will return a sample of the asteroid Bennu to Earth. The sample will land via parachute in the Utah desert.