The 11-day mission was the second flight of the Wake Shield Facility (WSF), a saucer-shaped satellite that was to fly free of the Shuttle for several days. The purpose of the WSF was to grow thin films in a near perfect vacuum created by the wake of the satellite as it moved through space. The crew also deployed and retrieved the Spartan 201 astronomy satellite, performed a six-hour spacewalk to test assembly techniques for the international Space Station and tested thermal improvements made to spacesuits used during space walks.

The Spartan 201 free-flyer made its third flight aboard the Shuttle. The Spartan 201 mission was a scientific research effort aimed at the investigation of the interaction between the Sun and its outflowing wind of charged particles. Spartan's goal was to study the outer atmosphere of the Sun and its transition into the solar wind that constantly flows past the Earth.