Soyuz 35 was a 1980 Soviet crewed space flight to the Salyut 6 space station. It was the 10th mission to and eighth successful docking at the orbiting facility. The Soyuz 35 crew were the fourth long-duration crew to man the space station.

Cosmonauts Leonid Popov and Valery Ryumin spent 185 days in space, setting a new space endurance record. Ryumin had completed a previous mission only eight months before. They hosted four visiting crews, including the first Hungarian, Cuban and Vietnamese cosmonauts. As long-duration crews now routinely swapped spacecraft with incoming crew, the Soyuz 35 craft was used to return the visiting Soyuz 36 crew to Earth, while the resident crew returned in Soyuz 37.

This is Soyuz's 53rd flight, and 34th crewed flight.

The Soyuz is a Soviet crewed spaceship, developed to made manned lunar missions. This version called 7K will fly 4 times on the giant launcher N1, and several tens of times on Proton to fly over the Moon, which will be successful during the mission Zond 4. Soyuz will become the first spacecraft to transport living beings to the Moon during the flight of Zond 5, with two turtles. Subsequently, it is adapted to low orbit and will fly on the Soyuz launcher to serve the Salyut and Mir stations and the ISS.