Soyuz TM-34 was a Russian Soyuz TM passenger transportation craft. It carried two cosmonauts and a South African tourist, Mark Shuttleworth, to the International Space Station (ISS). Shuttleworth performed some biology experiments, as he carried a live rat and sheep stem cells. All three returned on Soyuz TM-33 after an eight-day mission.

Soyuz TM-34 was the final flight of the Soyuz-TM variant, due to its replacement by the upgraded Soyuz-TMA. It was also the last crewed vehicle to launch atop the Soyuz-U rocket, although the Soyuz-U continued to launch uncrewed vehicles until 2017.

The Soyuz is a Soviet crewed spaceship, developed to made crewed lunar missions. This version called 7K will fly 4 times on the giant launcher N1, and several tens of times on Proton to fly over the Moon, which will be successful during the mission Zond 4. Soyuz will become the first spacecraft to transport living beings to the Moon during the flight of Zond 5, with two turtles. Subsequently, it is adapted to low orbit and will fly on the Soyuz launcher to serve the Salyut and Mir stations and the ISS.