Soyuz TMA-18M was a 2015 Soyuz spaceflight to the International Space Station. It provided the two twelve-months occupants (Scott Kelly and Mikhail Korniyenko) at the International Space Station with a fresh Soyuz capsule. TMA-18M was the 127th flight of a Soyuz spacecraft; the first having occurred in 1967. The ascent flight consisted of a Russian commander and two flight engineers from Denmark (ESA) and Kazakhstan respectively. The flight launched in September 2015 and returned to Earth in March 2016.

The Kazakh Aidyn Aimbetov is of the first Kazakh cosmonaut class, and the first to fly. The ESA astronaut Andreas Mogensen became the first Dane in space.

The descent crew was the same Russian commander and the two twelve-months occupants in March 2016. Two of the ascent crew members returned to Earth with Soyuz TMA-16M in September 2015.

The Soyuz is a Soviet crewed spacecraft, developed to perform lunar missions with crew. This version called 7K will fly 4 times on the giant launcher N1, and several tens of times on Proton to fly over the Moon, which will be successful during the mission Zond 4. Soyuz will become the first spacecraft to transport living beings on the Moon during the flight of Zond 5, with two turtles. Thereafter, it is adapted to the low orbit and will fly on the Soyuz launcher to supply the Soviet Salyut and Mir stations, and the ISS.