Soyuz TMA-15M was a 2014 flight to the International Space Station. It transported three members of the Expedition 42 crew to the International Space Station. TMA-15M was the 124th flight of a Soyuz spacecraft, the first flight launching in 1967. The Soyuz remained docked to the space station for the Expedition 43 increment, serving as an emergency escape vehicle until departing and returning to Earth as scheduled in June 2015.

The Soyuz is a Soviet crewed spacecraft, developed to perform lunar missions with crew. This version called 7K will fly 4 times on the giant launcher N1, and several tens of times on Proton to fly over the Moon, which will be successful during the mission Zond 4. Soyuz will become the first spacecraft to transport living beings on the Moon during the flight of Zond 5, with two turtles. Thereafter, it is adapted to the low orbit and will fly on the Soyuz launcher to supply the Soviet Salyut and Mir stations, and the ISS.